4a4l
From Proteopedia
CRYSTAL STRUCTURE OF POLO-LIKE KINASE 1 IN COMPLEX WITH A 5-(2-AMINO- PYRIMIDIN-4-YL)-1H-PYRROLE INHIBITOR
Template:ABSTRACT PUBMED 22154349
About this Structure
4a4l is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Caruso M, Valsasina B, Ballinari D, Bertrand J, Brasca MG, Caldarelli M, Cappella P, Fiorentini F, Gianellini LM, Scolaro A, Beria I. 5-(2-Amino-pyrimidin-4-yl)-1H-pyrrole and 2-(2-amino-pyrimidin-4-yl)-1,5,6,7-tetrahydro-pyrrolo[3,2-c]pyridin-4-one derivatives as new classes of selective and orally available Polo-like kinase 1 inhibitors. Bioorg Med Chem Lett. 2012 Jan 1;22(1):96-101. Epub 2011 Nov 23. PMID:22154349 doi:10.1016/j.bmcl.2011.11.065
