2lkx

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Image:2lkx.jpg

Template:STRUCTURE 2lkx

NMR structure of the homeodomain of Pitx2 in complex with a TAATCC DNA binding site

Template:ABSTRACT PUBMED 15895993

About this Structure

2lkx is a 3 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 1yz8. Full experimental information is available from OCA.

Reference

  • Chaney BA, Clark-Baldwin K, Dave V, Ma J, Rance M. Solution structure of the K50 class homeodomain PITX2 bound to DNA and implications for mutations that cause Rieger syndrome. Biochemistry. 2005 May 24;44(20):7497-511. PMID:15895993 doi:10.1021/bi0473253

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