1a0h

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Image:1a0h.png

Template:STRUCTURE 1a0h

THE X-RAY CRYSTAL STRUCTURE OF PPACK-MEIZOTHROMBIN DESF1: KRINGLE/THROMBIN AND CARBOHYDRATE/KRINGLE/THROMBIN INTERACTIONS AND LOCATION OF THE LINKER CHAIN

Template:ABSTRACT PUBMED 9438869

About this Structure

1a0h is a 4 chain structure with sequence from Bos taurus. The January 2002 RCSB PDB Molecule of the Month feature on Thrombin by David S. Goodsell is 10.2210/rcsb_pdb/mom_2002_1. Full crystallographic information is available from OCA.

Reference

  • Martin PD, Malkowski MG, Box J, Esmon CT, Edwards BF. New insights into the regulation of the blood clotting cascade derived from the X-ray crystal structure of bovine meizothrombin des F1 in complex with PPACK. Structure. 1997 Dec 15;5(12):1681-93. PMID:9438869
  • Bode W. The structure of thrombin: a janus-headed proteinase. Semin Thromb Hemost. 2006 Apr;32 Suppl 1:16-31. PMID:16673263 doi:10.1055/s-2006-939551

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