1r64

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Template:STRUCTURE 1r64

Contents

The 2.2 A crystal structure of Kex2 protease in complex with Ac-Arg-Glu-Lys-boroArg peptidyl boronic acid inhibitor

Template:ABSTRACT PUBMED 14992578

Function

[KEX2_YEAST] Processing of precursors of alpha-factors and killer toxin.

About this Structure

1r64 is a 4 chain structure with sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

  • Holyoak T, Kettner CA, Petsko GA, Fuller RS, Ringe D. Structural basis for differences in substrate selectivity in Kex2 and furin protein convertases. Biochemistry. 2004 Mar 9;43(9):2412-21. PMID:14992578 doi:10.1021/bi035849h

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