1b4k

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Template:STRUCTURE 1b4k

Contents

High resolution crystal structure of a MG2-dependent 5-aminolevulinic acid dehydratase

Template:ABSTRACT PUBMED 10356331

Function

[HEM2_PSEAE] Catalyzes an early step in the biosynthesis of tetrapyrroles. Binds two molecules of 5-aminolevulinate per subunit, each at a distinct site, and catalyzes their condensation to form porphobilinogen (By similarity).

About this Structure

1b4k is a 2 chain structure with sequence from Pseae. Full crystallographic information is available from OCA.

Reference

  • Frankenberg N, Erskine PT, Cooper JB, Shoolingin-Jordan PM, Jahn D, Heinz DW. High resolution crystal structure of a Mg2+-dependent porphobilinogen synthase. J Mol Biol. 1999 Jun 11;289(3):591-602. PMID:10356331 doi:10.1006/jmbi.1999.2808

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