3s4q
From Proteopedia
P38 alpha kinase complexed with a pyrazolo-triazine based inhibitor
Template:ABSTRACT PUBMED 21705217
About this Structure
3s4q is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Dyckman AJ, Li T, Pitt S, Zhang R, Shen DR, McIntyre KW, Gillooly KM, Shuster DJ, Doweyko AM, Sack JS, Kish K, Kiefer SE, Newitt JA, Zhang H, Marathe PH, McKinnon M, Barrish JC, Dodd JH, Schieven GL, Leftheris K. Discovery of pyrrolo[2,1-f][1,2,4]triazine C6-ketones as potent, orally active p38alpha MAP kinase inhibitors. Bioorg Med Chem Lett. 2011 Aug 1;21(15):4633-7. Epub 2011 May 30. PMID:21705217 doi:10.1016/j.bmcl.2011.05.091
