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4ddl

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Revision as of 07:30, 21 March 2012 by OCA (Talk | contribs)
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Image:4ddl.jpg

Template:STRUCTURE 4ddl

PDE10a Crystal Structure Complexed with Novel Inhibitor

Template:ABSTRACT PUBMED 22365755

About this Structure

4ddl is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Hu E, Kunz RK, Rumfelt S, Chen N, Burli R, Li C, Andrews KL, Zhang J, Chmait S, Kogan J, Lindstrom M, Hitchcock SA, Treanor J. Discovery of potent, selective, and metabolically stable 4-(pyridin-3-yl)cinnolines as novel phosphodiesterase 10A (PDE10A) inhibitors. Bioorg Med Chem Lett. 2012 Mar 15;22(6):2262-5. Epub 2012 Feb 8. PMID:22365755 doi:10.1016/j.bmcl.2012.01.086

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OCA

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