3vjm

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Image:3vjm.jpg

Template:STRUCTURE 3vjm

Crystal structure of human depiptidyl peptidase IV (DPP-4) in complex with a prolylthiazolidine inhibitor #1

Template:ABSTRACT PUBMED 22824762

About this Structure

3vjm is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Yoshida T, Akahoshi F, Sakashita H, Sonda S, Takeuchi M, Tanaka Y, Nabeno M, Kishida H, Miyaguchi I, Hayashi Y. Fused bicyclic heteroarylpiperazine-substituted l-prolylthiazolidines as highly potent DPP-4 inhibitors lacking the electrophilic nitrile group. Bioorg Med Chem. 2012 Aug 15;20(16):5033-41. Epub 2012 Jul 5. PMID:22824762 doi:10.1016/j.bmc.2012.06.033

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