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3t3m

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Revision as of 07:45, 28 March 2012 by OCA (Talk | contribs)
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Image:3t3m.jpg

Template:STRUCTURE 3t3m

A Novel High Affinity Integrin alphaIIbbeta3 Receptor Antagonist That Unexpectedly Displaces Mg2+ from the beta3 MIDAS

Template:ABSTRACT PUBMED 22422993

About this Structure

3t3m is a 8 chain structure with sequence from Homo sapiens and Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Zhu J, Choi WS, McCoy JG, Negri A, Zhu J, Naini S, Li J, Shen M, Huang W, Bougie D, Rasmussen M, Aster R, Thomas CJ, Filizola M, Springer TA, Coller BS. Structure-Guided Design of a High-Affinity Platelet Integrin alphaIIbbeta3 Receptor Antagonist That Disrupts Mg2+ Binding to the MIDAS. Sci Transl Med. 2012 Mar 14;4(125):125ra32. PMID:22422993 doi:10.1126/scitranslmed.3003576

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