2rs6

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Template:STRUCTURE 2rs6

Contents 1 Solution structure of the N-terminal dsRBD from RNA helicase A 2 Function 3 About this Structure 4 Reference

Solution structure of the N-terminal dsRBD from RNA helicase A

Template:ABSTRACT PUBMED 22454253

Function

[DHX9_MOUSE] Component of the CRD-mediated complex that promotes MYC mRNA stability. Unwinds double-stranded DNA and RNA in a 3' to 5' direction. Alterations of secondary structure may subsequently influence interactions with proteins or other nucleic acids. Functions as a transcriptional activator. Involved with LARP6 in the stabilization of type I collagen mRNAs for CO1A1 and CO1A2 (By similarity).

About this Structure

2rs6 is a 1 chain structure with sequence from Mus musculus. Full experimental information is available from OCA.

Reference

• Nagata T, Tsuda K, Kobayashi N, Shirouzu M, Kigawa T, Guntert P, Yokoyama S, Muto Y. Solution structures of the double-stranded RNA-binding domains from RNA helicase A. Proteins. 2012 Jun;80(6):1699-706. doi: 10.1002/prot.24059. Epub 2012 Mar 27. PMID:22454253 doi:http://dx.doi.org/10.1002/prot.24059