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3cv6

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Image:3cv6.png

Template:STRUCTURE 3cv6

The crystal structure of mouse 17-alpha hydroxysteroid dehydrogenase GG225.226PP mutant in complex with inhibitor and cofactor NADP+.

Template:ABSTRACT PUBMED 19237748

About this Structure

3cv6 is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

  • Dhagat U, Endo S, Mamiya H, Hara A, El-Kabbani O. Structure of the G225P/G226P mutant of mouse 3(17)alpha-hydroxysteroid dehydrogenase (AKR1C21) ternary complex: implications for the binding of inhibitor and substrate. Acta Crystallogr D Biol Crystallogr. 2009 Mar;65(Pt 3):257-65. Epub 2009, Feb 20. PMID:19237748 doi:10.1107/S0907444908044028

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