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Kinesin

Introduction

Kinesins are a class of motor proteins found in eukaryotic cells which are capable of converting chemical energy to mechanical work by hydrolyzing ATP. These motor proteins are essential in transporting molecules that are incapable of reaching their proper destinations by passive methods (e.g. diffusion) but require more active methods of transport like the use of molecular motors. Kinesins are composed of a motor domain, which binds ATP and hydrolyzes it to ADP converting that chemical energy into motion, and a cargo-binding domain which holds the species being transported. A long flexible stem connects the cargo-binding domain to the motor domain. Most Kinesins transport large cargo like lysosomes from the nucleus toward to the peripheral or the membrane using the array of microtubles found in the cell. This is my active site