NAC transcription factor

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Vascular-related NAC-domain transcription factor

Overview

Vascular-related NAC-domain transcription facor (VND)is one group of the largest plant-specific transcription factor NAC family. The VND1-VND7 were orginally isolated as genes for which expression levels are elevated during transdifferentiation into trachery elements, in a induction system using Arabidopsis suspension cells [1].VNDs are grouped in NAC-c subfamily [2]. Typically, the proteins in this subfamily share a well conserved N-terminal NAC domain (-150 amino acid;aa) and a diversified C-terminal transcription regulatory region [3,4]. The N-terminal NAC domain is usually responsible for DNA binding and dimerization, and the C-terminal NAC domain function in transcription activation , repression and protein binding.




1.Kubo M,Udagawa M, Nishikubo N, Horiguchi G, Yamaguchi M, Ito J, Mimura T, Fukuda H, and Demura T (2005) Transcription swtiches for protoxylem and metaxylem vessel formation. Gene Dev.16, 1855-1860.

2.Shen H, Yin Y, Chen F, Xu Y,and Dixon R (2009)A bioinformatic analysis of NAC genes for plant cell wall development in relation to lignocellulosic bioenergy production. Bioener.Res. 2,217-232.

3.Olsen A N, Ernst H A, Leggio L L,and Skriver K (2005) NAC transcription factor : structurally distinct, functionally diverse. Trends Plant Sci. 10,79-87

4.Ernst H A, Olsen A N, Skriver K, Larsen S,and Leggio L L (2004)Structure of the conserved domain of ANAC,a member of the NAC family of transcription factors. EMBO J 5,297-303

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Hao Chen, Alexander Berchansky, Michal Harel, David Canner, Jaime Prilusky, OCA

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