3vrw

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Image:3vrw.jpg

Template:STRUCTURE 3vrw

VDR ligand binding domain in complex with 22S-Butyl-2-methylidene-26,27-dimethyl-19,24-dinor-1alpha,25-dihydroxyvitamin D3

Template:ABSTRACT PUBMED 22512505

About this Structure

3vrw is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

  • Yoshimoto N, Sakamaki Y, Haeta M, Kato A, Inaba Y, Itoh T, Nakabayashi M, Ito N, Yamamoto K. Butyl pocket formation in the vitamin d receptor strongly affects the agonistic or antagonistic behavior of ligands. J Med Chem. 2012 May 10;55(9):4373-81. Epub 2012 Apr 27. PMID:22512505 doi:10.1021/jm300230a

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