4ere
From Proteopedia
crystal structure of MDM2 (17-111) in complex with compound 23
Template:ABSTRACT PUBMED 22524527
About this Structure
4ere is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Rew Y, Sun D, Gonzalez-Lopez De Turiso F, Bartberger MD, Beck HP, Canon J, Chen A, Chow D, Deignan J, Fox BM, Gustin D, Huang X, Jiang M, Jiao X, Jin L, Kayser F, Kopecky DJ, Li Y, Lo MC, Long AM, Michelsen K, Oliner JD, Osgood T, Ragains M, Saiki AY, Schneider S, Toteva M, Yakowec P, Yan X, Ye Q, Yu D, Zhao X, Zhou J, Medina JC, Olson SH. Structure-Based Design of Novel Inhibitors of the MDM2-p53 Interaction. J Med Chem. 2012 May 9. PMID:22524527 doi:10.1021/jm300354j