4aof
From Proteopedia
Selective small molecule inhibitor discovered by chemoproteomic assay platform reveals regulation of Th17 cell differentiation by PI3Kgamma
Template:ABSTRACT PUBMED 22544264
About this Structure
4aof is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
Reference
- Bergamini G, Bell K, Shimamura S, Werner T, Cansfield A, Muller K, Perrin J, Rau C, Ellard K, Hopf C, Doce C, Leggate D, Mangano R, Mathieson T, O'Mahony A, Plavec I, Rharbaoui F, Reinhard F, Savitski MM, Ramsden N, Hirsch E, Drewes G, Rausch O, Bantscheff M, Neubauer G. A selective inhibitor reveals PI3Kgamma dependence of T(H)17 cell differentiation. Nat Chem Biol. 2012 Apr 29;8(6):576-82. doi: 10.1038/nchembio.957. PMID:22544264 doi:10.1038/nchembio.957
Categories: Homo sapiens | Bantscheff, M. | Bell, K. | Bergamini, G. | Cansfield, A. | Doce, C. | Drewes, G. | Ellard, K. | Hirsch, E. | Hopf, C. | Leggate, D. | Mangano, R. | Mathieson, T. | Muller, K. | Neubauer, G. | Omahony, A. | Perrin, J. | Plavec, I. | Ramsden, N. | Rau, C. | Rausch, O. | Reinhard, F. | Rharbaoui, F. | Savitski, M M. | Shimamura, S. | Werner, T. | Transferase
