4e1g

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Template:STRUCTURE 4e1g

X-ray crystal structure of alpha-linolenic acid bound to the cyclooxygenase channel of cyclooxygenase-2

Template:ABSTRACT PUBMED 22637474

About this Structure

4e1g is a 2 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

Vecchio AJ, Orlando BJ, Nandagiri R, Malkowski MG. Investigating substrate promiscuity in cyclooxygenase-2: the role of Arg-120 and residues lining the hydrophobic groove. J Biol Chem. 2012 May 25. PMID:22637474 doi:10.1074/jbc.M112.372243

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Categories: Mus musculus | Prostaglandin-endoperoxide synthase | Malkowski, M G. | Vecchio, A J. | Biological dimer | Cox-2 | Membrane of er | Monotopic membrane protein | N-glycosylation | Oxidoreductase

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