2w26
From Proteopedia
Contents |
Fator Xa in complex with BAY59-7939
Template:ABSTRACT PUBMED 16161994
About this Structure
2w26 is a 2 chain structure of Factor Xa with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Roehrig S, Straub A, Pohlmann J, Lampe T, Pernerstorfer J, Schlemmer KH, Reinemer P, Perzborn E. Discovery of the novel antithrombotic agent 5-chloro-N-({(5S)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939): an oral, direct factor Xa inhibitor. J Med Chem. 2005 Sep 22;48(19):5900-8. PMID:16161994 doi:10.1021/jm050101d
Categories: Homo sapiens | Lampe, T. | Pernerstorfer, J. | Perzborn, E. | Pohlmann, J. | Reinemer, P. | Roehrig, S. | Schaefer, M. | Schlemmer, K. | Straub, A. | Blood coagulation | Cleavage on pair of basic residue | Egf-like domain | Factor xa | Gamma-carboxyglutamic acid | Glycoprotein | Hydrolase | Hydroxylation | Protease | Secreted | Serine protease | Zymogen
