3u15

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Image:3u15.png

Template:STRUCTURE 3u15

Structure of hDMX with Dimer Inducing Indolyl Hydantoin RO-2443

Template:ABSTRACT PUBMED 22745160

About this Structure

3u15 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

  • Graves B, Thompson T, Xia M, Janson C, Lukacs C, Deo D, Di Lello P, Fry D, Garvie C, Huang KS, Gao L, Tovar C, Lovey A, Wanner J, Vassilev LT. Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization. Proc Natl Acad Sci U S A. 2012 Jul 17;109(29):11788-93. Epub 2012 Jun 28. PMID:22745160 doi:10.1073/pnas.1203789109

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