4dvz

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Template:STRUCTURE 4dvz

Contents 1 Crystal structure of the Helicobacter pylori CagA oncoprotein 2 Function 3 About this Structure 4 Reference

Crystal structure of the Helicobacter pylori CagA oncoprotein

Template:ABSTRACT PUBMED 22817985

Function

[CAGA_HELPY] May be necessary for the transcription, folding, export, or function of the cytotoxin.

About this Structure

4dvz is a 1 chain structure with sequence from Helicobacter pylori 26695. Full crystallographic information is available from OCA.

Reference

• Hayashi T, Senda M, Morohashi H, Higashi H, Horio M, Kashiba Y, Nagase L, Sasaya D, Shimizu T, Venugopalan N, Kumeta H, Noda NN, Inagaki F, Senda T, Hatakeyama M. Tertiary Structure-Function Analysis Reveals the Pathogenic Signaling Potentiation Mechanism of Helicobacter pylori Oncogenic Effector CagA. Cell Host Microbe. 2012 Jul 19;12(1):20-33. PMID:22817985 doi:10.1016/j.chom.2012.05.010