4f9d

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Template:STRUCTURE 4f9d

Contents 1 Structure of Escherichia coli PgaB 42-655 in complex with nickel 2 Function 3 About this Structure 4 Reference

Structure of Escherichia coli PgaB 42-655 in complex with nickel

Template:ABSTRACT PUBMED 22810235

Function

[PGAB_ECOLI] Catalyzes the N-deacetylation of poly-beta-1,6-N-acetyl-D-glucosamine (PGA), a biofilm adhesin polysaccharide. N-deacetylation promotes PGA export through the PgaA porin.^{[1] [2]}

About this Structure

4f9d is a 2 chain structure with sequence from Escherichia coli k-12. Full crystallographic information is available from OCA.

Reference

• Little DJ, Poloczek J, Whitney JC, Robinson H, Nitz M, Howell PL. The structure- and metal-dependent activity of Escherichia coli PgaB provides insight into the partial de-N-acetylation of poly-beta-1,6-N-acetyl-D-glucosamine. J Biol Chem. 2012 Sep 7;287(37):31126-37. doi: 10.1074/jbc.M112.390005. Epub 2012, Jul 18. PMID:22810235 doi:10.1074/jbc.M112.390005

1. ↑ Wang X, Preston JF 3rd, Romeo T. The pgaABCD locus of Escherichia coli promotes the synthesis of a polysaccharide adhesin required for biofilm formation. J Bacteriol. 2004 May;186(9):2724-34. PMID:15090514
2. ↑ Itoh Y, Rice JD, Goller C, Pannuri A, Taylor J, Meisner J, Beveridge TJ, Preston JF 3rd, Romeo T. Roles of pgaABCD genes in synthesis, modification, and export of the Escherichia coli biofilm adhesin poly-beta-1,6-N-acetyl-D-glucosamine. J Bacteriol. 2008 May;190(10):3670-80. doi: 10.1128/JB.01920-07. Epub 2008 Mar, 21. PMID:18359807 doi:10.1128/JB.01920-07