2aw1

From Proteopedia

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Template:STRUCTURE 2aw1

Contents 1 Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor Celecoxib 2 About this Structure 3 See Also 4 Reference

Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor Celecoxib

Template:ABSTRACT PUBMED 16290146

About this Structure

2aw1 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Carbonic anhydrase

Reference

• Di Fiore A, Pedone C, D'Ambrosio K, Scozzafava A, De Simone G, Supuran CT. Carbonic anhydrase inhibitors: Valdecoxib binds to a different active site region of the human isoform II as compared to the structurally related cyclooxygenase II "selective" inhibitor celecoxib. Bioorg Med Chem Lett. 2006 Jan 15;16(2):437-42. Epub 2005 Nov 14. PMID:16290146 doi:10.1016/j.bmcl.2005.09.040