4dbs

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Template:STRUCTURE 4dbs

Contents 1 Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) in complex with NADP+ and 3'-[(4-nitronaphthalen-1-yl)amino]benzoic acid 2 About this Structure 3 See Also 4 Reference

Crystal structure of human 17beta-hydroxysteroid dehydrogenase type 5 (AKR1C3) in complex with NADP+ and 3'-[(4-nitronaphthalen-1-yl)amino]benzoic acid

Template:ABSTRACT PUBMED 22507964

About this Structure

4dbs is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Hydroxysteroid dehydrogenase

Reference

• Chen M, Adeniji AO, Twenter BM, Winkler JD, Christianson DW, Penning TM. Crystal structures of AKR1C3 containing an N-(aryl)amino-benzoate inhibitor and a bifunctional AKR1C3 inhibitor and androgen receptor antagonist. Therapeutic leads for castrate resistant prostate cancer. Bioorg Med Chem Lett. 2012 Mar 29. PMID:22507964 doi:10.1016/j.bmcl.2012.03.085