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8fab

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Template:STRUCTURE 8fab

Contents

CRYSTAL STRUCTURE OF THE FAB FRAGMENT FROM THE HUMAN MYELOMA IMMUNOGLOBULIN IGG HIL AT 1.8 ANGSTROMS RESOLUTION

Template:ABSTRACT PUBMED 2015229

About this Structure

8fab is a 4 chain structure of Antibody with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Strong RK, Campbell R, Rose DR, Petsko GA, Sharon J, Margolies MN. Three-dimensional structure of murine anti-p-azophenylarsonate Fab 36-71. 1. X-ray crystallography, site-directed mutagenesis, and modeling of the complex with hapten. Biochemistry. 1991 Apr 16;30(15):3739-48. PMID:2015229
  • Saul FA, Poljak RJ. Structural patterns at residue positions 9, 18, 67 and 82 in the VH framework regions of human and murine immunoglobulins. J Mol Biol. 1993 Mar 5;230(1):15-20. PMID:8450531 doi:http://dx.doi.org/10.1006/jmbi.1993.1121
  • Richardson JS, Richardson DC. Natural beta-sheet proteins use negative design to avoid edge-to-edge aggregation. Proc Natl Acad Sci U S A. 2002 Mar 5;99(5):2754-9. PMID:11880627 doi:10.1073/pnas.052706099

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