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1dna

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Image:1dna.png

Template:STRUCTURE 1dna

Contents

D221(169)N MUTANT DOES NOT PROMOTE OPENING OF THE COFACTOR IMIDAZOLIDINE RING

Template:ABSTRACT PUBMED 9753479

About this Structure

1dna is a 2 chain structure of Thymidylate synthase with sequence from Escherichia coli. Full crystallographic information is available from OCA.

See Also

Reference

  • Sage CR, Michelitsch MD, Stout TJ, Biermann D, Nissen R, Finer-Moore J, Stroud RM. D221 in thymidylate synthase controls conformation change, and thereby opening of the imidazolidine. Biochemistry. 1998 Sep 29;37(39):13893-901. PMID:9753479 doi:10.1021/bi9810510

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OCA

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