3imx

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Template:STRUCTURE 3imx

Contents 1 Crystal Structure of human glucokinase in complex with a synthetic activator 2 About this Structure 3 See Also 4 Reference

Crystal Structure of human glucokinase in complex with a synthetic activator

Template:ABSTRACT PUBMED 19746978

About this Structure

3imx is a 1 chain structure of Hexokinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Hexokinase

Reference

• Bebernitz GR, Beaulieu V, Dale BA, Deacon R, Duttaroy A, Gao J, Grondine MS, Gupta RC, Kakmak M, Kavana M, Kirman LC, Liang J, Maniara WM, Munshi S, Nadkarni SS, Schuster HF, Stams T, St Denny I, Taslimi PM, Vash B, Caplan SL. Investigation of functionally liver selective glucokinase activators for the treatment of type 2 diabetes. J Med Chem. 2009 Oct 8;52(19):6142-52. PMID:19746978 doi:10.1021/jm900839k