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2g01

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Image:2g01.png

Template:STRUCTURE 2g01

Contents

Pyrazoloquinolones as Novel, Selective JNK1 inhibitors

Template:ABSTRACT PUBMED 16527482

About this Structure

2g01 is a 4 chain structure of Mitogen-activated protein kinase with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

Reference

  • Liu M, Xin Z, Clampit JE, Wang S, Gum RJ, Haasch DL, Trevillyan JM, Abad-Zapatero C, Fry EH, Sham HL, Liu G. Synthesis and SAR of 1,9-dihydro-9-hydroxypyrazolo[3,4-b]quinolin-4-ones as novel, selective c-Jun N-terminal kinase inhibitors. Bioorg Med Chem Lett. 2006 May 15;16(10):2590-4. Epub 2006 Mar 9. PMID:16527482 doi:http://dx.doi.org/10.1016/j.bmcl.2006.02.046

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