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3g42
From Proteopedia
Contents |
Crystal Structure of TACE with Tryptophan Sulfonamide Derivative Inhibitor
Template:ABSTRACT PUBMED 19410464
About this Structure
3g42 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.
See Also
Reference
- Park K, Gopalsamy A, Aplasca A, Ellingboe JW, Xu W, Zhang Y, Levin JI. Synthesis and activity of tryptophan sulfonamide derivatives as novel non-hydroxamate TNF-alpha converting enzyme (TACE) inhibitors. Bioorg Med Chem. 2009 Jun 1;17(11):3857-65. Epub 2009 Apr 22. PMID:19410464 doi:10.1016/j.bmc.2009.04.033
Categories: ADAM 17 endopeptidase | Homo sapiens | Aplasca, A. | Gopalsamy, A. | K., Park. | Levin, J I. | Xu, W. | Zhang, Y H. | Cleavage on pair of basic residue | Glycoprotein | Hydrolase | Membrane | Metal-binding | Metalloprotease | Notch signaling pathway | Phosphoprotein | Protease | Sh3-binding | Tace-inhibitor complex | Tace/adam-17 | Transmembrane | Zn-endopeptidase | Zymogen
