1i5r

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Template:STRUCTURE 1i5r

Contents 1 TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EM1745 COMPLEX 2 About this Structure 3 See Also 4 Reference

TYPE 1 17-BETA HYDROXYSTEROID DEHYDROGENASE EM1745 COMPLEX

Template:ABSTRACT PUBMED 12223444

About this Structure

1i5r is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Hydroxysteroid dehydrogenase

Reference

• Qiu W, Campbell RL, Gangloff A, Dupuis P, Boivin RP, Tremblay MR, Poirier D, Lin SX. A concerted, rational design of type 1 17beta-hydroxysteroid dehydrogenase inhibitors: estradiol-adenosine hybrids with high affinity. FASEB J. 2002 Nov;16(13):1829-31. Epub 2002 Sep 5. PMID:12223444 doi:10.1096/fj.02-0026fje
• Schuster D, Nashev LG, Kirchmair J, Laggner C, Wolber G, Langer T, Odermatt A. Discovery of nonsteroidal 17beta-hydroxysteroid dehydrogenase 1 inhibitors by pharmacophore-based screening of virtual compound libraries. J Med Chem. 2008 Jul 24;51(14):4188-99. Epub 2008 Jun 6. PMID:18533708 doi:10.1021/jm800054h