This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
3en7
From Proteopedia
Contents |
Targeted polypharmacology: crystal structure of the c-Src kinase domain in complex with S1, a multitargeted kinase inhibitor
Template:ABSTRACT PUBMED 18849971
About this Structure
3en7 is a 2 chain structure of Proto-oncogene tyrosine-protein kinase with sequence from Gallus gallus. Full crystallographic information is available from OCA.
See Also
Reference
- Apsel B, Blair JA, Gonzalez B, Nazif TM, Feldman ME, Aizenstein B, Hoffman R, Williams RL, Shokat KM, Knight ZA. Targeted polypharmacology: discovery of dual inhibitors of tyrosine and phosphoinositide kinases. Nat Chem Biol. 2008 Nov;4(11):691-9. Epub 2008 Oct 12. PMID:18849971 doi:http://dx.doi.org/10.1038/nchembio.117
Categories: Gallus gallus | Non-specific protein-tyrosine kinase | Apsel, B. | Blair, J A. | Knight, Z A. | Shokat, K M. | Atp-binding | Inhibitor | Kinase | Kinase-inhibitor complex | Lipoprotein | Multitarget | Myristate | Nucleotide-binding | Phosphoinositide | Phosphoprotein | Polypharmacology | Proto-oncogene | Pyrazolopyrimidine | Sh2 domain | Sh3 domain | Signaling | Src | Transferase | Tyrosine | Tyrosine-protein kinase
