1h9p
From Proteopedia
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CRYSTAL STRUCTURE OF DIOCLEA GUIANENSIS SEED LECTIN
Overview
Diocleinae legume lectins are a group of oligomeric proteins whose, subunits display a high degree of primary structure and tertiary fold, conservation but exhibit considerable diversity in their oligomerisation, modes. To elucidate the structural determinants underlaying Diocleinae, lectin oligomerisation, we have determined the crystal structures of, native and cadmium-substituted Dioclea guianensis (Dguia) seed lectin., These structures have been solved by molecular replacement using, concanavalin (ConA) coordinates as the starting model, and refined against, data to 2.0 A resolution. In the native (Mn/Ca-Dguia) crystal form, (P4(3)2(1)2), the asymmetric unit contains two monomers arranged into a, canonical legume lectin dimer, and the tetramer is formed with a, symmetry-related dimer. ... [(full description)]
About this Structure
1H9P is a [Single protein] structure of sequence from [Dioclea guianensis] with CD and MN as [ligands]. Structure known Active Sites: AC1, AC2, AC3, AC4, AC5 and AC6. Full crystallographic information is available from [OCA].
Reference
Crystal structure of native and Cd/Cd-substituted Dioclea guianensis seed lectin. A novel manganese-binding site and structural basis of dimer-tetramer association., Wah DA, Romero A, Gallego del Sol F, Cavada BS, Ramos MV, Grangeiro TB, Sampaio AH, Calvete JJ, J Mol Biol. 2001 Jul 20;310(4):885-94. PMID:11453695
Page seeded by OCA on Tue Oct 30 15:33:05 2007
