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4dwx

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Template:STRUCTURE 4dwx

Contents

Crystal Structure of a Family GH-19 Chitinase from rye seeds

Template:ABSTRACT PUBMED 22831795

Function

[CHIC_SECCE] Defense against chitin containing fungal pathogens. Binds the hyphal tips of fungi and degrades nascent chitin.[1] [2] [3]

About this Structure

4dwx is a 2 chain structure with sequence from Secale cereale. Full crystallographic information is available from OCA.

Reference

  • Ohnuma T, Numata T, Osawa T, Inanaga H, Okazaki Y, Shinya S, Kondo K, Fukuda T, Fukamizo T. Crystal structure and chitin oligosaccharide-binding mode of a "loopful" family GH19 chitinase from rye, Secale cereal, seeds. FEBS J. 2012 Jul 25. doi: 10.1111/j.1742-4658.2012.08723.x. PMID:22831795 doi:10.1111/j.1742-4658.2012.08723.x
  1. Ohnuma T, Yagi M, Yamagami T, Taira T, Aso Y, Ishiguro M. Molecular cloning, functional expression, and mutagenesis of cDNA encoding rye (Secale cereale) seed chitinase-c. Biosci Biotechnol Biochem. 2002 Feb;66(2):277-84. PMID:11999399
  2. Taira T, Yamagami T, Aso Y, Ishiguro M, Ishihara M. Localization, accumulation, and antifungal activity of chitinases in rye (Secale cereale) seed. Biosci Biotechnol Biochem. 2001 Dec;65(12):2710-8. PMID:11826968
  3. Taira T, Ohnuma T, Yamagami T, Aso Y, Ishiguro M, Ishihara M. Antifungal activity of rye (Secale cereale) seed chitinases: the different binding manner of class I and class II chitinases to the fungal cell walls. Biosci Biotechnol Biochem. 2002 May;66(5):970-7. PMID:12092848

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