Sandbox reserved 392

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Aminoglycoside 2'-N-acetyltransferase from Mycobacterium tuberculosis-Complex with Coenzyme A and Tobramycin

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Describe the PDB (ligand/protein)

This Shows the possibility that the high affinity aminoglycoside complexes may have the capability to acetylate a key biosynthetic intermediate of mycothiol. Mycothiol is a major reducing agent in the myobacteria. If this occurs it may participate in the regulation of cellular redox potential.

Reference: Vetting, M. W., et al. "Aminoglycoside 2'-N-acetyltransferase from Mycobacterium 

    tuberculosis-Complex with Coenzyme A and Tobramycin." RCSB Protien Data Base. N.p., 28 Aug. 
    2002. Web. 13 July 2011. <http://www.rcsb.org/pdb/explore/explore.do?structureId=1M4D>.

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