4feu
From Proteopedia
Crystal structure of the aminoglycoside phosphotransferase APH(3')-Ia, with substrate kanamycin and small molecule inhibitor anthrapyrazolone SP600125
Template:ABSTRACT PUBMED 23758273
About this Structure
4feu is a 6 chain structure with sequence from Acinetobacter baumannii aye. Full crystallographic information is available from OCA.
Reference
- Stogios PJ, Spanogiannopoulos P, Evdokimova E, Egorova O, Shakya T, Todorovic N, Capretta A, Wright GD, Savchenko A. Structure-guided optimization of protein kinase inhibitors reverses aminoglycoside antibiotic resistance. Biochem J. 2013 Jun 12. PMID:23758273 doi:10.1042/BJ20130317
Categories: Acinetobacter baumannii aye | Kanamycin kinase | Anderson, W F. | CSGID, Center for Structural Genomics of Infectious Diseases. | Egorova, O. | Evdokimova, E. | Leo, R Di. | Minasov, G. | Savchenko, A. | Shakya, T. | Spanogiannopoulos, P. | Stogios, P J. | Wawrzak, Z. | Wright, G D. | Alpha/beta protein | Aminoglycoside phosphotransferase | Aminoglycoside | Anthrapyrazolone | Antibiotic resistance | Center for structural genomics of infectious disease | Csgid | Eukaryotic protein kinase-like fold | Gtp | Intracellular | Kanamycin | National institute of allergy and infectious disease | Niaid | Phosphotransferase | Protein kinase inhibitor | Sp600125 | Transferase | Transferase-transferase inhibitor complex
