Publication Abstract from PubMed
The biphenyl amides (BPAs) are a novel series of p38 MAP kinase inhibitors. The discovery of the series through structure-based focused screening is described, and the binding mode of the compounds is explained with reference to X-ray crystal structures.
Biphenyl amide p38 kinase inhibitors 1: Discovery and binding mode.,Angell RM, Bamborough P, Cleasby A, Cockerill SG, Jones KL, Mooney CJ, Somers DO, Walker AL Bioorg Med Chem Lett. 2008 Jan 1;18(1):318-23. Epub 2007 Nov 19. PMID:18006306[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
