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3vmk

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Template:STRUCTURE 3vmk

Contents

3-isopropylmalate dehydrogenase from Shewanella benthica DB21 MT-2

Template:ABSTRACT PUBMED 22442218

Function

[D2YZL2_9GAMM] Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate (By similarity).[RuleBase:RU004445][HAMAP-Rule:MF_01033][SAAS:SAAS001804_004_020645]

About this Structure

3vmk is a 2 chain structure with sequence from Shewanella benthica. Full crystallographic information is available from OCA.

Reference

  • Nagae T, Kato C, Watanabe N. Structural analysis of 3-isopropylmalate dehydrogenase from the obligate piezophile Shewanella benthica DB21MT-2 and the nonpiezophile Shewanella oneidensis MR-1. Acta Crystallogr Sect F Struct Biol Cryst Commun. 2012 Mar 1;68(Pt 3):265-8. Epub, 2012 Feb 15. PMID:22442218 doi:10.1107/S1744309112001443

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