This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2wbe

From Proteopedia

Revision as of 11:17, 24 July 2013 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 2wbe

Contents

Kinesin-5-Tubulin Complex with AMPPNP

Template:ABSTRACT PUBMED 19285086

Function

[TBA1A_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain. [KL61_DROME] Important role in mitotic dividing cells. Microtubule motor required for spindle body separation. Slow plus-end directed microtubule motor capable of cross-linking and sliding apart antiparallel microtubules, thereby pushing apart the associated spindle poles during spindle assembly and function. [TBB_PIG] Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

About this Structure

2wbe is a 3 chain structure with sequence from Bos taurus and Drosophila melanogaster. Full crystallographic information is available from OCA.

See Also

Reference

  • Bodey AJ, Kikkawa M, Moores CA. 9-Angstrom structure of a microtubule-bound mitotic motor. J Mol Biol. 2009 May 1;388(2):218-24. Epub 2009 Mar 10. PMID:19285086 doi:10.1016/j.jmb.2009.03.008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2wbe"
Personal tools