1v4s

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spinqualitylabelsall models PDB ID 1v4s Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
1v4s, resolution 2.30Å ()
Ligands:	, ,
Activity:	Hexokinase, with EC number 2.7.1.1
Related:	1v4t
Structural annotation: Resources: InterPro : Ipr001312 Pfam : PF00349, PF03727 SCOP : d1v4sa2, d1v4sa1 UniProt : P35557
Functional annotation: Biological process: glucose homeostasis detection of glucose positive regulation of glycogen biosynthetic process glucose metabolic process glycolysis negative regulation of gluconeogenesis positive regulation of insulin secretion Molecular function: glucokinase activity kinase activity nucleotide binding hexokinase activity transferase activity ATP binding protein binding glucose binding
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Contents 1 Crystal structure of human glucokinase 2 About this Structure 3 See Also 4 Reference

Crystal structure of human glucokinase

Template:ABSTRACT PUBMED 15016359

About this Structure

1v4s is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Hexokinase

Reference

• Kamata K, Mitsuya M, Nishimura T, Eiki J, Nagata Y. Structural basis for allosteric regulation of the monomeric allosteric enzyme human glucokinase. Structure. 2004 Mar;12(3):429-38. PMID:15016359 doi:10.1016/j.str.2004.02.005