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3t72

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Template:STRUCTURE 3t72

Contents

PhoB(E)-Sigma70(4)-(RNAP-Betha-flap-tip-helix)-DNA Transcription Activation Sub-Complex

Template:ABSTRACT PUBMED 21829166

Function

[RPOD_ECOLI] Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This is the primary sigma factor of this bacterium. [PHOB_ECOLI] This protein is a positive regulator for the phosphate regulon. Transcription of this operon is positively regulated by PhoB and PhoR when phosphate is limited.

About this Structure

3t72 is a 50 chain structure with sequence from Ecoli. Full crystallographic information is available from OCA.

See Also

Reference

  • Blanco AG, Canals A, Bernues J, Sola M, Coll M. The structure of a transcription activation subcomplex reveals how sigma(70) is recruited to PhoB promoters. EMBO J. 2011 Aug 9;30(18):3776-85. doi: 10.1038/emboj.2011.271. PMID:21829166 doi:10.1038/emboj.2011.271

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OCA

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