2oxu

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spinqualitylabelsall models PDB ID 2oxu Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image
2oxu, resolution 1.24Å ()
Ligands:	,
Gene:	MMP12, HME (Homo sapiens)
Activity:	Macrophage elastase, with EC number 3.4.24.65
Related:	1y93, 1rmz, 2oxw, 2oxz, 2oy2, 2oy4
Structural annotation: Resources: InterPro : Ipr000585, Ipr006025, Ipr002477, Ipr001818, Ipr006026 Pfam : PF00413 UniProt : P39900
Functional annotation: Cellular component: proteinaceous extracellular matrix Biological process: metabolic process proteolysis cell motility Molecular function: metallopeptidase activity catalytic activity metal ion binding macrophage elastase activity peptidase activity hydrolase activity metalloendopeptidase activity calcium ion binding zinc ion binding
Evolutionary conservation: Toggle Conservation Colors: Rows = identical sequences: Further Information: Caveats, Explanation, Complete Results at ConSurfDB
Resources:	FirstGlance, OCA, RCSB, PDBsum
Coordinates:	save as pdb, mmCIF, xml

Contents 1 Uninhibited form of human MMP-12 2 About this Structure 3 See Also 4 Reference

Uninhibited form of human MMP-12

About this Structure

2oxu is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

See Also

• Elastase
• Matrix Metalloproteinase 12
• Matrix metalloproteinase

Reference

• Bertini I, Calderone V, Fragai M, Luchinat C, Maletta M, Yeo KJ. Snapshots of the reaction mechanism of matrix metalloproteinases. Angew Chem Int Ed Engl. 2006 Dec 4;45(47):7952-5. PMID:17096442 doi:10.1002/anie.200603100