4gex

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Template:STRUCTURE 4gex

Contents 1 Structure of a stabilised ceSAS-6 dimer, second crystal form 2 Function 3 About this Structure 4 Reference

Structure of a stabilised ceSAS-6 dimer, second crystal form

Function

[SAS6_CAEEL] Required for centrosome duplication. Participates in centriole assembly.^{[1] [2]}

About this Structure

4gex is a 4 chain structure with sequence from Caenorhabditis elegans. Full crystallographic information is available from OCA.

Reference

1. ↑ Dammermann A, Muller-Reichert T, Pelletier L, Habermann B, Desai A, Oegema K. Centriole assembly requires both centriolar and pericentriolar material proteins. Dev Cell. 2004 Dec;7(6):815-29. PMID:15572125 doi:S1534580704003806
2. ↑ Leidel S, Delattre M, Cerutti L, Baumer K, Gonczy P. SAS-6 defines a protein family required for centrosome duplication in C. elegans and in human cells. Nat Cell Biol. 2005 Feb;7(2):115-25. PMID:15665853 doi:ncb1220