Malarial Dihydrofolate Reductase as Drug Target
From Proteopedia
Introduction
There are currently antimalarial drugs that target the malarial dihydrofolate reductase (DHFR) such as pyrimethamine and cycloguanil. However, the effectiveness of these drugs has decreased because of mutations in the enzyme that have led to drug resistance.
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Proteopedia Page Contributors and Editors (what is this?)
Mary Smith, Alexander Berchansky, Karsten Theis, Michal Harel
