4baf

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Template:STRUCTURE 4baf

Contents

Hen egg-white lysozyme structure in complex with the europium tris- hydroxyethyltriazoledipicolinate complex at 1.51 A resolution.

Template:ABSTRACT PUBMED 23123834

Function

[LYSC_CHICK] Lysozymes have primarily a bacteriolytic function; those in tissues and body fluids are associated with the monocyte-macrophage system and enhance the activity of immunoagents. Has bacteriolytic activity against M.luteus.[1]

About this Structure

4baf is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA.

Reference

  • Talon R, Nauton L, Canet JL, Kahn R, Girard E, Gautier A. Clicked europium dipicolinate complexes for protein X-ray structure determination. Chem Commun (Camb). 2012 Nov 12;48(97):11886-8. doi: 10.1039/c2cc36982f. PMID:23123834 doi:10.1039/c2cc36982f
  1. Maehashi K, Matano M, Irisawa T, Uchino M, Kashiwagi Y, Watanabe T. Molecular characterization of goose- and chicken-type lysozymes in emu (Dromaius novaehollandiae): evidence for extremely low lysozyme levels in emu egg white. Gene. 2012 Jan 15;492(1):244-9. doi: 10.1016/j.gene.2011.10.021. Epub 2011 Oct, 25. PMID:22044478 doi:10.1016/j.gene.2011.10.021

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