1r8i
From Proteopedia
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| , resolution 3.00Å | |||||||
|---|---|---|---|---|---|---|---|
| Gene: | trac (Escherichia coli) | ||||||
| Coordinates: | save as pdb, mmCIF, xml | ||||||
Crystal structure of TraC
Overview
Type IV secretion systems mediate intercellular transfer of macro-molecules via a mechanism ancestrally related to that of bacterial conjugation machineries. TraC of the IncN plasmid pKM101 belongs to the VirB5 family of proteins, an essential component of most type IV secretion systems. Here, we present the structure of TraC. VirB5/TraC is a single domain protein, which consists of a three helix bundle and a loose globular appendage. Structure-based site-directed mutagenesis followed by functional studies indicates that VirB5 proteins participate in protein-protein interactions important for pilus assembly and function.
About this Structure
1R8I is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.
Reference
Structural and functional characterization of the VirB5 protein from the type IV secretion system encoded by the conjugative plasmid pKM101., Yeo HJ, Yuan Q, Beck MR, Baron C, Waksman G, Proc Natl Acad Sci U S A. 2003 Dec 23;100(26):15947-52. Epub 2003 Dec 12. PMID:14673074
Page seeded by OCA on Thu Mar 20 13:48:19 2008
Categories: Escherichia coli | Single protein | Baron, C. | Beck, M R. | Waksman, G. | Yeo, H J. | Yuan, Q. | Helical bundle | Trac | Virb5
