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1rbp

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Revision as of 11:49, 20 March 2008 by OCA (Talk | contribs)
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PDB ID 1rbp

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, resolution 2.0Å
Ligands:
Coordinates: save as pdb, mmCIF, xml



CRYSTALLOGRAPHIC REFINEMENT OF HUMAN SERUM RETINOL BINDING PROTEIN AT 2 ANGSTROMS RESOLUTION


Contents

Overview

Human serum retinol binding protein (RBP) in complex with retinol has been crystallographically refined to an R-factor of 18.1% with 2A resolution data. The protein topology results in an anti-parallel beta-barrel that encapsulates the retinol ligand. A detailed description of the protein and the binding site is provided. Our structural work has helped to define a family of proteins, many of which are carrier proteins for smaller ligand molecules. We describe the structural basis for the conservation of sequence within the family.

Disease

Known disease associated with this structure: Retinol binding protein, deficiency of OMIM:[180250]

About this Structure

1RBP is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Crystallographic refinement of human serum retinol binding protein at 2A resolution., Cowan SW, Newcomer ME, Jones TA, Proteins. 1990;8(1):44-61. PMID:2217163

Page seeded by OCA on Thu Mar 20 13:49:26 2008

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