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3zcs
From Proteopedia
Contents |
Rabbit muscle glycogen phosphorylase b in complex with N-(1-naphthoyl) -N-beta-D-glucopyranosyl urea determined at 2.07 A resolution
Template:ABSTRACT PUBMED 11895439
Function
[PYGM_RABIT] Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.
About this Structure
3zcs is a 1 chain structure with sequence from Oryctolagus cuniculus. Full crystallographic information is available from OCA.
Reference
- Oikonomakos NG, Kosmopoulou M, Zographos SE, Leonidas DD, Chrysina ED, Somsak L, Nagy V, Praly JP, Docsa T, Toth B, Gergely P. Binding of N-acetyl-N '-beta-D-glucopyranosyl urea and N-benzoyl-N '-beta-D-glucopyranosyl urea to glycogen phosphorylase b: kinetic and crystallographic studies. Eur J Biochem. 2002 Mar;269(6):1684-96. PMID:11895439
Categories: Oryctolagus cuniculus | Phosphorylase | Alexacou, K M. | Chrysina, E D. | Docsa, T. | Felfoldi, N. | Gergely, P. | Hayes, J M. | Kardakaris, R. | Konstantakaki, M. | Konya, B. | Leonidas, D D. | Nagy, V. | Oikonomakos, N G. | Praly, J P. | Somsak, L. | Telepo, K. | Zographos, S E. | Hypoglycaemic agent | Inhibitor | Structure-based ligand design | Transferase
