4i03

From Proteopedia

Revision as of 11:20, 24 April 2013 by OCA (Talk | contribs)
Jump to: navigation, search

Template:STRUCTURE 4i03

Human MMP12 in complex with a PEG-linked bifunctional L-glutamate motif inhibitor

Template:ABSTRACT PUBMED 23567804

Function

[MMP12_HUMAN] May be involved in tissue injury and remodeling. Has significant elastolytic activity. Can accept large and small amino acids at the P1' site, but has a preference for leucine. Aromatic or hydrophobic residues are preferred at the P1 site, with small hydrophobic residues (preferably alanine) occupying P3.

About this Structure

4i03 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools