1nfk is a 4 chain structure with sequence from Mus musculus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
Publication Abstract from PubMed
The 2.3-A crystal structure of the transcription factor NK-kappa B p50 homodimer bound to a palindromic kappa B site reveals that the Rel homology region folds into two distinct domains, similar to those in the immunoglobulin superfamily. The p50 dimer envelopes an undistorted B-DNA helix, making specific contacts along the 10-base-pair kappa B recognition site mainly through loops connecting secondary structure elements in both domains. The carboxy-terminal domains form a dimerization interface between beta-sheets using residues that are strongly conserved in the Rel family.
Structure of NF-kappa B p50 homodimer bound to a kappa B site.,Ghosh G, van Duyne G, Ghosh S, Sigler PB Nature. 1995 Jan 26;373(6512):303-10. PMID:7530332[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
↑ Ghosh G, van Duyne G, Ghosh S, Sigler PB. Structure of NF-kappa B p50 homodimer bound to a kappa B site. Nature. 1995 Jan 26;373(6512):303-10. PMID:7530332 doi:http://dx.doi.org/10.1038/373303a0
