4hti

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Template:STRUCTURE 4hti

Contents 1 Crystallographic structure of the membrane-proximal ectodomain of the human receptor-type protein-tyrosine phosphatase phogrin 2 Function 3 About this Structure 4 Reference

Crystallographic structure of the membrane-proximal ectodomain of the human receptor-type protein-tyrosine phosphatase phogrin

Template:ABSTRACT PUBMED 23016632

Function

[PTPR2_HUMAN] Implicated in development of nervous system and pancreatic endocrine cells.^{[1] [2]}

About this Structure

4hti is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

• Noguera ME, Primo ME, Sosa LN, Risso VA, Poskus E, Ermacora MR. Biophysical Characterization of the Membrane-proximal Ectodomain of the Receptor-type Protein-tyrosine Phosphatase Phogrin. Protein Pept Lett. 2012 Sep 25. PMID:23016632

1. ↑ Kawasaki E, Hutton JC, Eisenbarth GS. Molecular cloning and characterization of the human transmembrane protein tyrosine phosphatase homologue, phogrin, an autoantigen of type 1 diabetes. Biochem Biophys Res Commun. 1996 Oct 14;227(2):440-7. PMID:8878534 doi:S0006-291X(96)91526-0
2. ↑ Cui L, Yu WP, DeAizpurua HJ, Schmidli RS, Pallen CJ. Cloning and characterization of islet cell antigen-related protein-tyrosine phosphatase (PTP), a novel receptor-like PTP and autoantigen in insulin-dependent diabetes. J Biol Chem. 1996 Oct 4;271(40):24817-23. PMID:8798755