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Contents 1 Alzheimer's amyloid precursor protein copper-binding domain 1.1 introduction 1.2 Biological role 1.3 structure 1.4 medical implication 1.5 additionnal resources 1.6 References

Alzheimer's amyloid precursor protein copper-binding domain

introduction

Biological role

structure

2fkl is constituted by two chains called A and B. Both chains have the same length and the same organization. Each chain also contains an alpha helix going from the residues 147 to 159 packed against a triple-strand beta sheet. The Beta 1 going from residues 133-139, the Beta 2 going from residues 162-167, and the Beta 3 going from residues 181 to 188. There is one more Beta sheet, B0, formed by the residues 127 to 139 of the B chain ...a compléter...

medical implication

additionnal resources

References

spinqualitylabelsall models Insert caption here Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image

Cys-133 and Cys-187 links strands β1 and β3